RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-29a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
RT-qPCR; dual-luciferase reporter assay
Target
DNMT3A
Pathway
NA
PubMed ID
Title
MicroRNA-29a inhibits cardiac fibrosis in Sprague-Dawley rats by downregulating the expression of DNMT3A
Year
2018
Function
miR-29a reduced the activation and proliferation of cardiac fibroblasts (CFs) to improve cardiac fibrosis probably by the downregulation of DNMT3A.